In October 17th's "Word of the Day" is written: "Los contratiempos que él ha experimentado en su vida lo han terminado de derrotar."
This is a truly a grammar question - I'm not trying to correct or criticize - is "...lo han..." correct or should it be "...los han..." since I think it's referring to "los contratiempos" that have beaten him?
Similar question for "Los hombres lo que hablan..." vs. "Los hombres los que hablan..."